Objective:In order to solve the problem of medical equipment image retrieval，an image retrievalmethod based on multi feature layer fusion is proposed. Process:This method using color moments to calculate thecharacteristics of color image，the LBP Operator is used to calculate the texture features of the image，using Fourierdescriptors calculated image of the characters，the stratified weighted fusion method of the characteristics of threetypes of fusion within a similarity measure，and ultimately the formation of retrieval based on. Results andconclusions:According to the experimental study of the endoscopic image and CT image，the experimental resultsconfirm the validity of the proposed method. With continuous improvement of the precision requirements of theproposed method in precision ratio was significantly higher than that of two single feature retrieval method formedical image retrieval.