Based on the multi-channel and high-speed digitization features of front-end readout circuits for biomedical imaging

a 16-channel pipeline digitization circuits is designed.The whole circuits consist of analog multiplexer

single end to differential signal conversion circuit

8-bit 25-Msample/s pipeline ADC

and data output module.Analog-to-digital conversion and data output will be executed in the pipeline way.The circuit is designed in TSMC 0.18 μm mixed signal CMOS technology.Simulation results show that

pipeline ADC has-0.62/0.67 LSB DNL

-0.39/0.72 LSB INL

45.99 dB SNR

and 6.03 bit ENOB.The designed circuits can accomplish the digitization and output of 16-channel analog signals within two adjacent timing windows

satisfying the performance requirements of the system.