By utilizing fully the shared L3 Cache

private L2 Cache and L1 Cache on the multi-core architecture

the produced large-scale data with the different combination of positions are distributed to the multi-level caches while the Modeling algorithm is used to solve -Motif finding problem

and a cache-efficient thread-level parallel -Motif finding algorithm is designed on multi-core computer by binding the threads to the cores to balance their computational loads. The experimental results show that

compared with the existing parallel algorithm to solve -Motif finding problem

the presented algorithm is efficient and has good speedup and scalability

and it can solve successfully the -Motif finding problem with longer l.