This study investigates the peristaltic motion of magnetohydrodynamic (MHD) couple-stress ternary nanofluids through an inclined asymmetric porous channel under the influence of Darcy-Forchheimer drag. Two blood-based ternary nanofluid formulations are considered: T1 (Ag+TiO

2

+Cu) and T2 (Au+Fe

3

O

4

+multi-walled carbon nanotube

MWCNT). Two ternary nanofluid combinations (Ag+TiO

2

+Cu and (Au+Fe

3

O

4

+multi-walled carbon nanotube

MWCNT) were selected to compare metallic-oxide blends with hybrid magnetic-carbon structures

enabling assessment of their distinct thermal and rheological advantages. The governing equations of momentum

energy

and concentration are developed under the long wavelength and low Reynolds number assumptions and transformed into a dimensionless form. The effects of couple stress

magnetic field

porosity

heat generation

and chemical reaction are examined using a shooting technique coupled with the classical fourth-order Runge-Kutta (RK-4) method. Results show that the magnetic field and Forchheimer effects increase flow resistance

while higher Darcy numbers enhance velocity and thermal performance. Ternary nanofluid-2 exhibits superior thermal and mass transfer rates due to the synergistic influence of Au

Fe

3

O

4

and MWCNT nanoparticles

which offer higher conductivity and low

er interfacial resistance. The outcomes provide physical insights relevant to biomedical pumping

targeted drug transport

and thermal regulation in microfluidic devices. A cubic regression model is used because it captures nonlinear interactions among magnetic

porous

and couple-stress parameters more accurately than linear or quadratic models

enabling reliable prediction of complex peristaltic flow behavior.