This paper addresses the scientific problems in bearing accelerated life test

such as lack of multi-stress acceleration model

and not well understanding of failure law. Firstly

the interface micro failure mode and mechanism of fluid lubricated bearing under environment of vacuum

temperature

preload

speed and microgravity are analyzed. Secondly

the micro contact uniform lubrication model considering multi-stress comprehensive working mechanism is derivated and established

and the numerical solution method based on improved Newton Raphson method is proposed. Thirdly

the orthogonal simulation scheme with 5 factors and 5 levels orthogonal table is designed

the bearing failure law in the work of vacuum

temperature

preload

speed and microgravity is simulated and analyzed

and the failure response value of micro contact surface film thickness

pressure peak

friction factor

maximum undersurface stress which changes with the stress level and contact region dimension is obtained. Finally

the multi-stress acceleration model about vacuum

temperature

preload

speed and microgravity based on response surface method has been established

which is verified by a test of actual engineering example.