1.西安理工大学计算机科学与工程学院,陕西 西安 710048
2.陕西省网络计算与安全技术重点实验室,陕西 西安 710048
3.人机共融智能机器人陕西省高校工程研究中心,陕西 西安 710048
[ "赵映程(1993- ),男,甘肃平凉人,博士,西安理工大学讲师,主要研究方向为计算机视觉、医学影像处理。" ]
[ "宋霄罡(1987- ),男,河南漯河人,博士,西安理工大学教授、博士生导师,主要研究方向为计算机视觉、无人系统自主导航。" ]
[ "石争浩(1968- ),男,陕西渭南人,博士,西安理工大学教授、博士生导师,主要研究方向为机器视觉、医学图像处理及机器学习。" ]
[ "尤珍臻(1989- ),女,陕西西安人,博士,西安理工大学讲师,主要研究方向为生物医学图像处理、机器学习。" ]
[ "黑新宏(1976- ),男,陕西延安人,博士,西安理工大学教授、博士生导师,主要研究方向为智能系统与安全关键系统、人工智能、大数据及其在轨道交通等系统中的应用。" ]
收稿:2025-11-01,
修回:2026-02-26,
录用:2026-02-26,
纸质出版:2026-04-20
移动端阅览
赵映程,宋霄罡,石争浩等.医学影像无监督异常检测技术综述[J].通信学报,2026,47(04):248-269.
Zhao Yingcheng,Song Xiaogang,Shi Zhenghao,et al.Review of unsupervised anomaly detection techniques for medical imaging[J].Journal on Communications,2026,47(04):248-269.
赵映程,宋霄罡,石争浩等.医学影像无监督异常检测技术综述[J].通信学报,2026,47(04):248-269. DOI: 10.11959/j.issn.1000-436x.2026046.
Zhao Yingcheng,Song Xiaogang,Shi Zhenghao,et al.Review of unsupervised anomaly detection techniques for medical imaging[J].Journal on Communications,2026,47(04):248-269. DOI: 10.11959/j.issn.1000-436x.2026046.
无监督异常检测技术能够在仅使用正常样本训练的前提下识别偏离分布的异常样本,因此在医学影像领域中能够用于病变的自动检测与区域定位,对辅助疾病筛查,尤其是罕见病的诊断具有重要意义。针对医学影像无监督异常检测领域的研究进展,首先,依据核心检测机制将现有异常检测方法划分为4个主要类别,并详细阐述了每类方法的机理、特性及其代表性工作;其次,汇总了常用的医学影像公开数据集,并归纳了主要的异常评分计算方式以及模型评估基准指标;进而,通过在多模态医学影像数据集上的系统性定量实验,对比了各类代表性方法的检测性能与计算效率,并对其结果进行了深入分析;最后,讨论了该领域在检测性能及临床适用性等方面存在的挑战,并对未来的研究方向进行了展望。
Unsupervised anomaly detection technology enabled the identification of out-of-distribution anomalous samples using only normal samples for training. Thus
it could be applied in the field of medical imaging for automated lesion detection and localization
playing a significant role in assisting disease screening
particularly in the diagnosis of rare diseases. Research progress on unsupervised anomaly detection in medical imaging. First
existing anomaly detection methods were categorized into four main types based on their core detection mechanisms
and the principles
characteristics
and representative works of each category were elaborated in detail. Second
commonly used public medical imaging datasets were summarized
and major anomaly scoring methods as well as benchmark evaluation metrics were introduced. Furthermore
through systematic quantitative experiments on multi-modal medical image datasets
the detection performance and computational efficiency of various representative methods were compared
and an in-depth analysis was provided based on the results. Finally
challenges in detection performance and clinical applicability were discussed
and future research directions were outlined.
Bergmann P , Fauser M , Sattlegger D , et al . MVTec AD: a comprehensive real-world dataset for unsupervised anomaly detection [C ] // Proceedings of the 2019 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR) . Piscataway : IEEE Press , 2019 : 9584 - 9592 .
王文鹏 , 秦寅畅 , 师文轩 . 工业缺陷检测无监督深度学习方法综述 [J ] . 计算机应用 , 2025 , 45 ( 5 ): 1658 - 1670 .
Wang W P , Qin Y C , Shi W X . Review of unsupervised deep learning methods for industrial defect detection [J ] . Journal of Computer Applications , 2025 , 45 ( 5 ): 1658 - 1670 .
尚书一 , 李宏佳 , 宋晨 , 等 . 互联网服务场景下基于机器学习的KPI异常检测综述 [J ] . 计算机研究与发展 , 2025 , 62 ( 1 ): 207 - 231 .
Shang S Y , Li H J , Song C , et al . Survey of machine learning-based KPI anomaly detection on Internet-based services [J ] . Journal of Computer Research and Development , 2025 , 62 ( 1 ): 207 - 231 .
Liu W , Luo W X , Lian D Z , et al . Future frame prediction for anomaly detection-a new baseline [C ] // Proceedings of the 2018 IEEE/CVF Conference on Computer Vision and Pattern Recognition . Piscataway : IEEE Press , 2018 : 6536 - 6545 .
张振宇 , 綦小龙 , 肖琪 , 等 . 视频异常检测技术综述 [J ] . 激光杂志 , 2026 , 47 ( 2 ): 1 - 15 .
Zhang Z Y , Qi X L , Xiao Q , et al . A survey on video anomaly detection techniques [J ] . Laser Journal , 2026 , 47 ( 2 ): 1 - 15 .
张赛男 , 孙彪 . 基于机器学习的网络异常检测方法综述 [J ] . 吉林大学学报(信息科学版) , 2021 , 39 ( 6 ): 732 - 742 .
Zhang S N , Sun B . Research on network anomaly detection method basedon machine learning [J ] . Journal of Jilin University (Information Science Edition) , 2021 , 39 ( 6 ): 732 - 742 .
Ruff L , Vandermeulen R A , Goernitz N , et al . Deep one-class classification [C ] // Proceedings of the 35th International Conference on Machine Learning . New York : PMLR , 2018 : 4393 - 4402 .
Hido S , Tsuboi Y , Kashima H , et al . Statistical outlier detection using direct density ratio estimation [J ] . Knowledge and Information Systems , 2011 , 26 ( 2 ): 309 - 336 .
Rousseeuw P J , Hubert M . Robust statistics for outlier detection [J ] . WIREs Data Mining and Knowledge Discovery , 2011 , 1 ( 1 ): 73 - 79 .
Knorr E M , Ng R T , Tucakov V . Distance-based outliers: algorithms and applications [J ] . The VLDB Journal the International Journal on Very Large Data Bases , 2000 , 8 ( 3/4 ): 237 - 253 .
Angiulli F , Basta S , Pizzuti C . Distance-based detection and prediction of outliers [J ] . IEEE Transactions on Knowledge and Data Engineering , 2006 , 18 ( 2 ): 145 - 160 .
Breunig M M , Kriegel H P , Ng R T , et al . LOF: identifying density-based local outliers [C ] // Proceedings of the 2000 ACM SIGMOD International Conference on Management of Data . New York : ACM Press , 2000 : 93 - 104 .
Yang X W , Latecki L J , Pokrajac D . Outlier detection with globally optimal exemplar-based GMM [C ] // Proceedings of the 2009 SIAM International Conference on Data Mining . Society for Industrial and Applied Mathematics , 2009 : 145 - 154 .
Al-Zoubi M B . An effective clustering-based approach for outlier detection [J ] . European Journal of Scientific Research , 2009 , 28 ( 2 ): 310 - 316 .
Akcay S , Atapour-Abarghouei A , Breckon T P . GANomaly: semi-supervised anomaly detection via adversarial training [C ] // Computer Vision-ACCV 2018 . Berlin : Springer , 2019 : 622 - 637 .
Schlegl T , Seeböck P , Waldstein S M , et al . F-AnoGAN: fast unsupervised anomaly detection with generative adversarial networks [J ] . Medical Image Analysis , 2019 , 54 : 30 - 44 .
Deng H Q , Li X Y . Anomaly detection via reverse distillation from one-class embedding [C ] // Proceedings of the 2022 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR) . Piscataway : IEEE Press , 2022 : 9727 - 9736 .
Tang P , Yan X X , Hu X B , et al . Anomaly detection in medical images using encoder-attention-2Decoders reconstruction [J ] . IEEE Transactions on Medical Imaging , 2025 , 44 ( 8 ): 3370 - 3382 .
Li C L , Sohn K , Yoon J , et al . CutPaste: self-supervised learning for anomaly detection and localization [C ] // Proceedings of the 2021 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR) . Piscataway : IEEE Press , 2021 : 9659 - 9669 .
Tan J , Hou B , Day T , et al . Detecting outliers with Poisson image interpolation [C ] // Proceedings of the Medical Image Computing and Computer Assisted Intervention-MICCAI 2021 . New York : ACM Press , 2021 : 581 - 591 .
Zavrtanik V , Kristan M , Skočaj D . DRÆM-A discriminatively trained reconstruction embedding for surface anomaly detection [C ] // Proceedings of the 2021 IEEE/CVF International Conference on Computer Vision (ICCV) . Piscataway : IEEE Press , 2021 : 8310 - 8319 .
Liu Z K , Zhou Y M , Xu Y S , et al . SimpleNet: a simple network for image anomaly detection and localization [C ] // Proceedings of the 2023 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR) . Piscataway : IEEE Press , 2023 : 20402 - 20411 .
Sohn K , Li C L , Yoon J , et al . Learning and evaluating representations for deep one-class classification [PP ] . arXiv ( 2020-11-04 ) [ 2025-11-01 ] . arXiv: arXiv. 2011 . 02578 .
Zhao H , Li Y X , He N J , et al . Anomaly detection for medical images using self-supervised and translation-consistent features [J ] . IEEE Transactions on Medical Imaging , 2021 , 40 ( 12 ): 3641 - 3651 .
Tian Y , Liu F B , Pang G S , et al . Self-supervised pseudo multi-class pre-training for unsupervised anomaly detection and segmentation in medical images [J ] . Medical Image Analysis , 2023 , 90 : 102930 .
Gong D , Liu L Q , Le V , et al . Memorizing normality to detect anomaly: memory-augmented deep autoencoder for unsupervised anomaly detection [C ] // Proceedings of the 2019 IEEE/CVF International Conference on Computer Vision (ICCV) . Piscataway : IEEE Press , 2019 : 1705 - 1714 .
Defard T , Setkov A , Loesch A , et al . PaDiM: a patch distribution modeling framework for anomaly detection and localization [C ] //Pattern Recognition. ICPR International Workshops and Challenges . Berlin : Springer , 2021 : 475 - 489 .
Kim T , Lee Y G , Jeong I , et al . Patch-wise vector quantization for unsupervised medical anomaly detection [J ] . Pattern Recognition Letters , 2024 , 184 : 205 - 211 .
Baur C , Denner S , Wiestler B , et al . Autoencoders for unsupervised anomaly segmentation in brain MR images: a comparative study [J ] . Medical Image Analysis , 2021 , 69 : 101952 .
侯金磊 . 基于卷积自编码器的脑MRI无监督异常检测算法研究 [D ] . 杭州 : 浙江大学 , 2021 .
Hou J L . Research on brain MRI Unsupervised anomaly detection algorithm based on convolutional autoencoder [D ] . Hangzhou : Zhejiang University , 2021 .
Hinton G E , Salakhutdinov R R . Reducing the dimensionality of data with neural networks [J ] . Science , 2006 , 313 ( 5786 ): 504 - 507 .
Goodfellow I J , Pouget-Abadie J , Mirza M , et al . Generative adversarial nets [J ] . Advances in Neural Information Processing Systems , 2014 , 2 : 2672 - 2680 .
Kingma D P , Welling M . Auto-encoding variational Bayes [PP ] . arXiv ( 2013-12-20 ) [ 2025-11-01 ] . arXiv:arXiv. 1312 . 6114 .
Milković F , Filipović B , Subasić M , et al . Ultrasound anomaly detection based on variational autoencoders [C ] // Proceedings of the 2021 12th International Symposium on Image and Signal Processing and Analysis (ISPA) . Piscataway : IEEE Press , 2021 : 225 - 229 .
Makhzani A , Shlens J , Jaitly N , et al . Adversarial autoencoders [PP ] . arXiv ( 2015-11-18 ) [ 2025-11-01 ] . arXiv:arXiv. 1511 . 05644 .
Zhang H B , Guo W P , Zhang S Q , et al . Unsupervised deep anomaly detection for medical images using an improved adversarial autoencoder [J ] . Journal of Digital Imaging , 2022 , 35 ( 2 ): 153 - 161 .
Meissen F , Wiestler B , Kaissis G , et al . On the pitfalls of using the residual error as anomaly score [C ] // Proceedings of the 5th International Conference on Medical Imaging with Deep Learning . New York : PMLR , 2022 : 914 - 928 .
Bergmann P , Löwe S , Fauser M , et al . Improving unsupervised defect segmentation by applying structural similarity to autoencoders [PP ] . arXiv ( 2018-07-05 ) [ 2025-11-01 ] . arXiv:arXiv. 1807 . 02011 .
Behrendt F , Bhattacharya D , Maack L , et al . Diffusion models with ensembled structure-based anomaly scoring for unsupervised anomaly detection [C ] // Proceedings of the 2024 IEEE International Symposium on Biomedical Imaging (ISBI) . Piscataway : IEEE Press , 2024 : 1 - 4 .
Shvetsova N , Bakker B , Fedulova I , et al . Anomaly detection in medical imaging with deep perceptual autoencoders [J ] . IEEE Access , 2021 , 9 : 118571 - 118583 .
Bercea C I , Rueckert D , Schnabel J A . What do AEs learn? Challenging common assumptions in unsupervised anomaly detection [C ] // Medical Image Computing and Computer Assisted Intervention-MICCAI 2023 . Berlin : Springer , 2023 : 304 - 314 .
Zimmerer D , Kohl S A A , Petersen J , et al . Context-encoding variational autoencoder for unsupervised anomaly detection [PP ] . arXiv ( 2018-12-14 ) [ 2025-11-01 ] . arXiv:arXiv. 1812 . 05941 .
Mao Y F , Xue F F , Wang R X , et al . Abnormality detection in chest X-ray images using uncertainty prediction autoencoders [C ] // Medical Image Computing and Computer Assisted Intervention-MICCAI 2020 . Berlin : Springer , 2020 : 529 - 538 .
Zhou X Y , Niu S J , Li X H , et al . Spatial-contextual variational autoencoder with attention correction for anomaly detection in retinal OCT images [J ] . Computers in Biology and Medicine , 2023 , 152 : 106328 .
Schlegl T , Seeböck P , Waldstein S M , et al . Unsupervised anomaly detection with generative adversarial networks to guide marker discovery [C ] // Information Processing in Medical Imaging . Berlin : Springer , 2017 : 146 - 157 .
Baur C , Wiestler B , Albarqouni S , et al . Deep autoencoding models for unsupervised anomaly segmentation in brain MR images [C ] // Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries . Berlin : Springer , 2019 : 161 - 169 .
Arjovsky M , Chintala S , Bottou L . Wasserstein generative adversarial networks [C ] // Proceedings of the 34th International Conference on Machine Learning -Volume 70 . New York : ACM Press , 2017 : 214 - 223 .
Han C , Rundo L , Murao K , et al . MADGAN: unsupervised medical anomaly detection GAN using multiple adjacent brain MRI slice reconstruction [J ] . BMC Bioinformatics , 2021 , 22 ( S2 ): 31 .
Li G L , Zou Y X , Liu B Y , et al . PAttL-GAN: pixel attention localization generative adversarial network for unsupervised anomaly detection in medical images [J ] . Neurocomputing , 2025 , 654 : 131345 .
Kascenas A , Pugeault N , O’Neil A Q . Denoising autoencoders for unsupervised anomaly detection in brain MRI [C ] // Proceedings of the International Conference on Medical Imaging with Deep Learning . New York : PMLR , 2022 : 653 - 664 .
Kascenas A , Sanchez P , Schrempf P , et al . The role of noise in denoising models for anomaly detection in medical images [J ] . Medical Image Analysis , 2023 , 90 : 102963 .
Ho J , Jain A , Abbeel P . Denoising diffusion probabilistic models [J ] . Advances in Neural Information Processing Systems , 2020 , 33 : 6840 - 6851 .
Behrendt F , Bhattacharya D , Krüger J , et al . Patched diffusion models for unsupervised anomaly detection in brain MRI [C ] // Proceedings of the Medical Imaging with Deep Learning . New York : PMLR , 2024 : 1019 - 1032 .
Bi Y , Huang L , Clarenbach R , et al . Synomaly noise and multi-stage diffusion: a novel approach for unsupervised anomaly detection in medical images [PP ] . arXiv ( 2024-11-06 ) [ 2025-11-01 ] . arXiv:arXiv. 2411 . 04004 .
Zhou B L , Khosla A , Lapedriza A , et al . Learning deep features for discriminative localization [C ] // Proceedings of the 2016 IEEE Conference on Computer Vision and Pattern Recognition (CVPR) . Piscataway : IEEE Press , 2016 : 2921 - 2929 .
Selvaraju R R , Cogswell M , Das A , et al . Grad-CAM: visual explanations from deep networks via gradient-based localization [C ] // Proceedings of the 2017 IEEE International Conference on Computer Vision (ICCV) . Piscataway : IEEE Press , 2017 : 618 - 626 .
Zimmerer D , Isensee F , Petersen J , et al . Unsupervised anomaly localization using variational auto-encoders [C ] // Medical Image Computing and Computer Assisted Intervention-MICCAI 2019 . Berlin : Springer , 2019 : 289 - 297 .
Liu W Q , Li R Z , Zheng M , et al . Towards visually explaining variational autoencoders [C ] // Proceedings of the 2020 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR) . Piscataway : IEEE Press , 2020 : 8639 - 8648 .
Silva-Rodríguez J , Naranjo V , Dolz J . Constrained unsupervised anomaly segmentation [J ] . Medical Image Analysis , 2022 , 80 : 102526 .
Krizhevsky A , Sutskever I , Hinton G E . ImageNet classification with deep convolutional neural networks [J ] . Communications of the ACM , 2017 , 60 ( 6 ): 84 - 90 .
Rippel O , Mertens P , Merhof D . Modeling the distribution of normal data in pre-trained deep features for anomaly detection [C ] // Proceedings of the 2020 25th International Conference on Pattern Recognition (ICPR) . Piscataway : IEEE Press , 2021 : 6726 - 6733 .
You Z Y , Yang K , Luo W H , et al . ADTR: anomaly detection transformer with feature reconstruction [C ] // Neural Information Processing . Berlin : Springer , 2023 : 298 - 310 .
Chen L Y , You Z Y , Zhang N , et al . UTRAD: anomaly detection and localization with U-Transformer [J ] . Neural Networks , 2022 , 147 : 53 - 62 .
You Z Y , Cui L , Shen Y J , et al . A unified model for multi-class anomaly detection [C ] // Proceedings of the 36th International Conference on Neural Information Processing Systems . New York : ACM Press , 2022 : 4571 - 4584 .
Lu S , Zhang W H , Zhao H , et al . Anomaly detection for medical images using heterogeneous auto-encoder [J ] . IEEE Transactions on Image Processing , 2024 , 33 : 2770 - 2782 .
Hinton G , Vinyals O , Dean J . Distilling the knowledge in a neural network [PP ] . arXiv ( 2015-03-09 ) [ 2025-11-01 ] . arXiv:arXiv. 1503 . 02531 .
Tien T D , Nguyen A T , Tran N H , et al . Revisiting reverse distillation for anomaly detection [C ] // Proceedings of the 2023 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR) . Piscataway : IEEE Press , 2023 : 24511 - 24520 .
Bergmann P , Fauser M , Sattlegger D , et al . Uninformed students: student-teacher anomaly detection with discriminative latent embeddings [C ] // Proceedings of the 2020 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR) . Piscataway : IEEE Press , 2020 : 4182 - 4191 .
Wang G D , Han S M , Ding E R , et al . Student-teacher feature pyramid matching for anomaly detection [PP ] . arXiv ( 2021-03-07 ) [ 2025-11-01 ] . arXiv:arXiv. 2103 . 04257 .
Salehi M , Sadjadi N , Baselizadeh S , et al . Multiresolution knowledge distillation for anomaly detection [C ] // Proceedings of the 2021 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR) . Piscataway : IEEE Press , 2021 : 14897 - 14907 .
Zhao Y Z , Ding Q Q , Zhang X Q . AE-FLOW: autoencoders with normalizing flows for medical images anomaly detection [C ] // The Eleventh International Conference on Learning Representations . Kigali : 2023 .
Liu M X , Jiao Y R , Lu J Q , et al . Anomaly detection for medical images using teacher-student model with skip connections and multiscale anomaly consistency [J ] . IEEE Transactions on Instrumentation and Measurement , 2024 , 73 : 2520415 .
Ge C K , Yu X J , Zheng H , et al . ESC-DRKD: enhanced skip connection-based direct reverse knowledge distillation for medical image anomaly detection [J ] . Neurocomputing , 2025 , 651 : 130994 .
Rahmaniar W , Suzuki K . Multi-AD: cross-domain unsupervised anomaly detection for medical and industrial applications [J ] . Pattern Recognition , 2026 , 172 : 112486 .
Guo J , Lu S , Jia L Z , et al . Encoder-decoder contrast for unsupervised anomaly detection in medical images [J ] . IEEE Transactions on Medical Imaging , 2024 , 43 ( 3 ): 1102 - 1112 .
Shi Y , Yang J , Qi Z Q . Unsupervised anomaly segmentation via deep feature reconstruction [J ] . Neurocomputing , 2021 , 424 : 9 - 22 .
Meissen F , Paetzold J , Kaissis G , et al . Unsupervised anomaly localization with structural feature-autoencoders [C ] // Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries . Berlin : Springer , 2023 : 14 - 24 .
Sato J , Suzuki Y , Wataya T , et al . Anatomy-aware self-supervised learning for anomaly detection in chest radiographs [J ] . IScience , 2023 , 26 ( 7 ): 107086 .
Tan J , Hou B , Batten J , et al . Detecting outliers with foreign patch interpolation [PP ] . arXiv ( 2020-11-09 ) [ 2025-11-01 ] . arXiv:arXiv. 2011 . 04197 .
Müller J P , Baugh M , Tan J , et al . Confidence-aware and self-supervised image anomaly localisation [C ] // Uncertainty for Safe Utilization of Machine Learning in Medical Imaging . Berlin : Springer , 2023 : 177 - 187 .
Schlüter H M , Tan J , Hou B , et al . Natural synthetic anomalies for self-supervised anomaly detection and localization [C ] // Computer Vision-ECCV 2022 . Berlin : Springer , 2022 : 474 - 489 .
Baugh M , Tan J , Müller J P , et al . Many tasks make light work: learning to localise medical anomalies from multiple synthetic tasks [C ] // Medical Image Computing and Computer Assisted Intervention-MICCAI 2023 . Berlin : Springer , 2023 : 162 - 172 .
Zhang X , Li S Y , Li X , et al . DeSTSeg: segmentation guided denoising student-teacher for anomaly detection [C ] // Proceedings of the 2023 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR) . Piscataway : IEEE Press , 2023 : 3914 - 3923 .
Cai Y X , Liang D K , Luo D L , et al . A discrepancy aware framework for robust anomaly detection [J ] . IEEE Transactions on Industrial Informatics , 2024 , 20 ( 3 ): 3986 - 3995 .
Zhang X M , Xu M , Zhou X Z . RealNet: a feature selection network with realistic synthetic anomaly for anomaly detection [C ] // Proceedings of the 2024 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR) . Piscataway : IEEE Press , 2024 : 16699 - 16708 .
Chen Q Y , Luo H Y , Lv C K , et al . A unified anomaly synthesis strategy with gradient ascent for industrial anomaly detection and localization [C ] // Computer Vision-ECCV 2024 . Berlin : Springer , 2024 : 37 - 54 .
Cai Y , Chen H , Yang X , et al . Dual-distribution discrepancy with self-supervised refinement for anomaly detection in medical images [J ] . Medical Image Analysis , 2023 , 86 : 102794 .
Chen X L , He K M . Exploring simple Siamese representation learning [C ] // Proceedings of the 2021 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR) . Piscataway : IEEE Press , 2021 : 15745 - 15753 .
Srivastava N , Mansimov E , Salakhutdinov R . Unsupervised learning of video representations using LSTMs [C ] // Proceedings of the 32nd International Conference on Machine Learning-Volume 37 . New York : ACM Press , 2015 : 843 - 852 .
Hjelm R D , Fedorov A , Lavoie-Marchildon S , et al . Learning deep representations by mutual information estimation and maximization [PP ] . arXiv ( 2018-08-20 ) [ 2025-11-01 ] . arXiv:arXiv. 1808 . 06670 .
Oord A V D , Li Y Z , Vinyals O . Representation learning with contrastive predictive coding [PP ] . arXiv ( 2018-07-11 ) [ 2025-11-01 ] . arXiv:arXiv. 1807 . 03748 .
Chen T , Kornblith S , Norouzi M , et al . A simple framework for contrastive learning of visual representations [C ] // International Conference on Machine Learning . New York : PMLR , 2020 : 1597 - 1607 .
He K , Fan H , Wu Y , et al . Momentum contrast for unsupervised visual representation learning [C ] // Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition . Piscataway : IEEE Press , 2020 : 9726 - 9735 .
Grill J B , Strub F , Altché F , et al . Bootstrap your own latent-a new approach to self-supervised learning [J ] . Advances in Neural Information Processing Systems , 2020 , 33 : 21271 - 21284 .
Schölkopf B , Platt J C , Shawe-Taylor J , et al . Estimating the support of a high-dimensional distribution [J ] . Neural Computation , 2001 , 13 ( 7 ): 1443 - 1471 .
Tax D M J , Duin R P W . Support vector data description [J ] . Machine Learning , 2004 , 54 ( 1 ): 45 - 66 .
Tian Y , Pang G S , Liu F B , et al . Constrained contrastive distribution learning for unsupervised anomaly detection and localisation in medical images [C ] // Medical Image Computing and Computer Assisted Intervention-MICCAI 2021 . Berlin : Springer , 2021 : 128 - 140 .
Lu S , Zhang W H , Guo J , et al . PatchCL-AE: anomaly detection for medical images using patch-wise contrastive learning-based auto-encoder [J ] . Computerized Medical Imaging and Graphics , 2024 , 114 : 102366 .
Reiss T , Hoshen Y . Mean-shifted contrastive loss for anomaly detection [J ] . Proceedings of the AAAI Conference on Artificial Intelligence , 2023 , 37 ( 2 ): 2155 - 2162 .
Roth K , Pemula L , Zepeda J , et al . Towards total recall in industrial anomaly detection [C ] // Proceedings of the 2022 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR) . Piscataway : IEEE Press , 2022 : 14298 - 14308 .
Zhou K , Li J , Luo W X , et al . Proxy-bridged image reconstruction network for anomaly detection in medical images [J ] . IEEE Transactions on Medical Imaging , 2022 , 41 ( 3 ): 582 - 594 .
Xiang T G , Zhang Y X , Lu Y Y , et al . SQUID: deep feature in-painting for unsupervised anomaly detection [PP ] . arXiv ( 2021-11-26 ) [ 2025-11-01 ] . arXiv:arXiv. 2111 . 13495 .
Zhou K , Li J , Xiao Y T , et al . Memorizing structure-texture correspondence for image anomaly detection [J ] . IEEE Transactions on Neural Networks and Learning Systems , 2022 , 33 ( 6 ): 2335 - 2349 .
Xiao Y F , Huang X T , Liang W , et al . Medical images anomaly detection for imbalanced datasets with multi-scale normalizing flow [J ] . Computer Science and Information Systems , 2025 , 22 ( 1 ): 219 - 238 .
Stein A , Wu C , Carr C , et al . RSNA pneumonia detection challenge [DS ] . [ 2025-11-01 ] .
Nguyen H Q , Lam K , Le L T , et al . VinDr-CXR: an open dataset of chest X-rays with radiologist’s annotations [J ] . Scientific Data , 2022 , 9 : 429 .
Hamada A . Br35H: brain tumor detection 2020 kaggle [DS ] . [ 2025-11-01 ] .
Nickparvar M . Brain tumor MRI dataset [DS ] . [ 2025-11-01 ] .
Kermany D S , Goldbaum M , Cai W J , et al . Identifying medical diagnoses and treatable diseases by image-based deep learning [J ] . Cell , 2018 , 172 ( 5 ): 1122 - 1131 .
Li L , Xu M , Wang X F , et al . Attention based glaucoma detection: a large-scale database and CNN model [C ] // Proceedings of the 2019 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR) . Piscataway : IEEE Press , 2019 : 10563 - 10572 .
Karthik , Maggie , Dane S . APTOS 2019 blindness detection [DS ] . [ 2025-11-01 ] .
Codella N , Rotemberg V , Tschandl P , et al . Skin lesion analysis toward melanoma detection 2018: a challenge hosted by the international skin imaging collaboration (ISIC) [PP ] . arXiv ( 2019-02-10 ) [ 2025-11-01 ] . arXiv:arXiv. 1902 . 03368 .
Bejnordi B E , Veta M , Diest P J V , et al . Diagnostic assessment of deep learning algorithms for detection of lymph node metastases in women with breast cancer [J ] . Jama , 2017 , 318 ( 22 ): 2199 - 2210 .
Zhao R Y , Yaman B , Zhang Y X , et al . FastMRI+, clinical pathology annotations for knee and brain fully sampled magnetic resonance imaging data [J ] . Scientific Data , 2022 , 9 : 152 .
Liew S L , Lo B P , Donnelly M R , et al . A large, curated, open-source stroke neuroimaging dataset to improve lesion segmentation algorithms [J ] . Scientific Data , 2022 , 9 : 320 .
Gao H H , Jiang W Y , Ran Q , et al . Vision-language interaction via contrastive learning for surface anomaly detection in consumer electronics manufacturing [J ] . IEEE Transactions on Consumer Electronics , 2024 , 70 ( 3 ): 6119 - 6130 .
Chen Y H , Tao H K , Yang Z , et al . Diffusion-based vision-language model for zero-shot anomaly detection in medical images [J ] . Engineering Applications of Artificial Intelligence , 2025 , 161 : 112181 .
Liu Y Y , Li Q Y , Wang Z H , et al . LECLIP: boosting zero-shot anomaly detection with local enhanced CLIP [J ] . IEEE Transactions on Instrumentation and Measurement , 2025 , 74 : 5034111 .
Yao M Y , Tao D , Qi P , et al . Rethinking discrepancy analysis: anomaly detection via meta-learning powered dual-source representation differentiation [J ] . IEEE Transactions on Automation Science and Engineering , 2025 , 22 : 8579 - 8592 .
García R , Aguilar J . A meta-learning approach in a cattle weight identification system for anomaly detection [J ] . Computers and Electronics in Agriculture , 2024 , 217 : 108572 .
Viana J S , Rosa E D L , Vyvere T V , et al . Unsupervised 3D brain anomaly detection [C ] // Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries . Berlin : Springer , 2021 : 133 - 142 .
Kang I , Park J . Joint embedding of 2D and 3D networks for medical image anomaly detection [PP ] . arXiv ( 2022-12-21 ) [ 2025-11-01 ] . arXiv:arXiv. 2212 . 10939 .
Marimont S N , Tarroni G . Implicit field learning for unsupervised anomaly detection in medical images [C ] // Medical Image Computing and Computer Assisted Intervention-MICCAI 2021 . Berlin : Springer , 2021 : 189 - 198 .
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